In-field genomic, transcriptomic and proteomic approaches to study emerging mosquito-borne viruses
Our field sites on the island of Sulawesi in Indonesia capture diverse habitats ranging from unspoiled tropical rain forests with high species diversity to highly urban environments with dense human populations. We are developing field-friendly approaches to study infectious disease emergence using cutting-edge high-throughput omic approaches ranging from genomics through transcriptomics to proteomics. Applying our experimental pipelines to real-world field settings allows us to study the molecular pathways that contribute to the emergence of new diseases into the human population in unprecedented detail. Our research primarily focusses on how habitat disruption at the urban-forest boundary alters the ability of mosquito vectors to transmit emerging arthropod-borne viruses.
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