Molecular and Cellular Mechanisms of Viral Haemorrhage

Many haemorrhagic fever viruses are neglected tropical diseases for which the underlying mechanisms contributing to the severe forms of haemorrhagic disease are poorly understood. Haemorrhage is caused by the disruption of the integrity of the blood vessels within the body’s circulatory system. We are collaborating with cardiovascular tissue engineers to better understand how haemorrhagic fever viruses, such as dengue virus, cause circulatory disruption. This research may eventually allow us to better diagnose which patients will suffer from haemorrhage, which could lead to better diagnostic assays and improved treatment options.

NTD Hub Members

Dr. Kevin Maringer

Dr. Paola Campagnolo

Mr. Yin Cheung

Locations

University of Surrey (Guildford, UK)