Many haemorrhagic fever viruses are neglected tropical diseases for which the underlying mechanisms contributing to the severe forms of haemorrhagic disease are poorly understood. Haemorrhage is caused by the disruption of the integrity of the blood vessels within the body’s circulatory system. We are collaborating with cardiovascular tissue engineers to better understand how haemorrhagic fever viruses, such as dengue virus, cause circulatory disruption. This research may eventually allow us to better diagnose which patients will suffer from haemorrhage, which could lead to better diagnostic assays and improved treatment options.
NTD Hub Members
Dr. Kevin Maringer
Dr. Paola Campagnolo
Mr. Yin Cheung
University of Surrey (Guildford, UK)