Dr Nicolas Locker


(SBM, dengue)

Research Interests

While we ask diverse research questions in the Locker lab, they all converge towards one over-arching theme: How do cells or pathogens maintain a specific translational programme in conditions where general translation is compromised or targeted for regulation?

Our main research interests are the regulation of gene expression and translational control during viral infection. We are trying to address fundamental questions at the interface between microbiology and RNA biology by asking how microbial genomes take control of the infected host protein synthesis machinery and how this impacts on the host translational landscape at the molecular and cellular level. We are also interested in other translational control mechanisms that impact on heath and diseases.

University of Surrey Profile